{
  "resourceType" : "ValueSet",
  "id" : "eHDSIMedicationStatusReason",
  "url" : "http://terminology.ehdsi.eu/ValueSet/eHDSIMedicationStatusReason",
  "identifier" : [{
    "system" : "urn:ietf:rfc:3986",
    "value" : "urn:oid:1.3.6.1.4.1.12559.11.10.1.3.1.42.97"
  }],
  "version" : "9.1.0",
  "name" : "EHDSIMedicationStatusReason",
  "title" : "eHDSI Medication Status Reason",
  "status" : "active",
  "experimental" : false,
  "date" : "2026-02-19T15:58:54+00:00",
  "publisher" : "MyHealth@Eu",
  "contact" : [{
    "name" : "MyHealth@Eu",
    "telecom" : [{
      "system" : "url",
      "value" : "https://health.ec.europa.eu/other-pages/basic-page/myhealtheu-flyer-addressed-patients-and-health-professionals_en"
    }]
  }],
  "description" : "The Value Set is used for coding reasons for the current state of the medication used.",
  "copyright" : "The Value Set incorporates SNOMED CT®, used by permission of the International Health Terminology Standards Development Organisation, trading as SNOMED International. SNOMED CT was originally created by the College of American Pathologists. SNOMED CT is a registered trademark of the International Health Terminology Standards Development Organisation, all rights reserved. For further information on the use of SNOMED CT, including translations, implementers of MyHealth@EU should review usage terms or directly contact SNOMED International: info@snomed.org.",
  "compose" : {
    "include" : [{
      "system" : "http://snomed.info/sct",
      "concept" : [{
        "code" : "106511000119106",
        "display" : "Long-term current use of mycophenolate"
      },
      {
        "code" : "106521000119104",
        "display" : "Long-term current use of cyclophosphamide"
      },
      {
        "code" : "106531000119101",
        "display" : "Long-term current use of penicillamine"
      },
      {
        "code" : "106571000119103",
        "display" : "Long-term current use of sulfasalazine"
      },
      {
        "code" : "106581000119100",
        "display" : "Long-term current use of cyclosporine"
      },
      {
        "code" : "106631000119102",
        "display" : "Long-term current use of infliximab"
      },
      {
        "code" : "106691000119103",
        "display" : "Long-term current use of etanercept"
      },
      {
        "code" : "106701000119103",
        "display" : "Long-term current use of leflunomide"
      },
      {
        "code" : "11012701000119107",
        "display" : "Long-term current use of antibiotics for prevention of recurrent infection"
      },
      {
        "code" : "11012741000119109",
        "display" : "Long-term current use of certolizumab pegol"
      },
      {
        "code" : "11281000175101",
        "display" : "Platelet aggregation inhibitor therapy declined"
      },
      {
        "code" : "113481000119108",
        "display" : "Long-term current use of tamoxifen"
      },
      {
        "code" : "113491000119106",
        "display" : "Long-term current use of deferasirox"
      },
      {
        "code" : "113521000119108",
        "display" : "Long term current use of adalimumab therapy"
      },
      {
        "code" : "113531000119106",
        "display" : "Long term current use of abatacept"
      },
      {
        "code" : "113541000119102",
        "display" : "Long-term current use of rituximab"
      },
      {
        "code" : "117431000119101",
        "display" : "Long term current use of drug therapy for attention deficit hyperactivity disorder"
      },
      {
        "code" : "118901000119102",
        "display" : "Long-term current use of erythropoiesis stimulating therapy"
      },
      {
        "code" : "118911000119104",
        "display" : "Long-term current use of lenalidomide"
      },
      {
        "code" : "118921000119106",
        "display" : "Long-term current use of clozapine"
      },
      {
        "code" : "118931000119109",
        "display" : "Long-term current use of intravenous immune globulin"
      },
      {
        "code" : "122621000119109",
        "display" : "Prophylactic anticoagulation given"
      },
      {
        "code" : "12275951000119104",
        "display" : "History of opiate therapy"
      },
      {
        "code" : "123371000119105",
        "display" : "Prophylactic aromatase inhibitors given"
      },
      {
        "code" : "12371000175103",
        "display" : "Drug treatment stopped patient ran out of medication"
      },
      {
        "code" : "12384021000119106",
        "display" : "Long-term current use of mercaptopurine"
      },
      {
        "code" : "123971000119106",
        "display" : "Long-term current use of acitretin"
      },
      {
        "code" : "123981000119109",
        "display" : "Long-term current use of isotretinoin"
      },
      {
        "code" : "125211000119106",
        "display" : "History of antineoplastic chemotherapy"
      },
      {
        "code" : "1269470004",
        "display" : "Missed dose"
      },
      {
        "code" : "126951000119109",
        "display" : "Long-term current use of lithium"
      },
      {
        "code" : "127721000119100",
        "display" : "Long-term current use of testosterone cypionate"
      },
      {
        "code" : "130721000119103",
        "display" : "Long-term current use of golimumab"
      },
      {
        "code" : "131531000119103",
        "display" : "Long-term current use of aspirin"
      },
      {
        "code" : "133621000119103",
        "display" : "Long term current use of non-steroidal anti-inflammatory drug"
      },
      {
        "code" : "134390006",
        "display" : "Angiotensin converting enzyme inhibitor not indicated"
      },
      {
        "code" : "134397009",
        "display" : "Angiotensin converting enzyme inhibitor declined"
      },
      {
        "code" : "1345106003",
        "display" : "Drug therapy discontinued due to pregnancy planning"
      },
      {
        "code" : "134651000119108",
        "display" : "History of estrogen therapy"
      },
      {
        "code" : "134671000119104",
        "display" : "History of systemic steroid therapy"
      },
      {
        "code" : "135794007",
        "display" : "Drug indicated"
      },
      {
        "code" : "135795008",
        "display" : "Nitrate indicated"
      },
      {
        "code" : "135796009",
        "display" : "Calcium channel blocker indicated"
      },
      {
        "code" : "135798005",
        "display" : "Diuretic indicated"
      },
      {
        "code" : "135799002",
        "display" : "Angiotensin converting enzyme inhibitor indicated"
      },
      {
        "code" : "135800003",
        "display" : "Aspirin indicated"
      },
      {
        "code" : "135801004",
        "display" : "Beta blocker indicated"
      },
      {
        "code" : "135803001",
        "display" : "Warfarin indicated"
      },
      {
        "code" : "139181000119106",
        "display" : "Long-term current use of amiodarone"
      },
      {
        "code" : "140301000119107",
        "display" : "Long-term current use of hydroxychloroquine"
      },
      {
        "code" : "140561000119102",
        "display" : "Long-term current use of azathioprine"
      },
      {
        "code" : "141381000119105",
        "display" : "Long-term current use of ambrisentan"
      },
      {
        "code" : "150881000119107",
        "display" : "Long-term current use of postmenopausal hormone replacement therapy"
      },
      {
        "code" : "152741000146103",
        "display" : "Medication spat out by patient"
      },
      {
        "code" : "15625371000119108",
        "display" : "Long-term current use of ustekinumab"
      },
      {
        "code" : "15625411000119109",
        "display" : "Long-term current use of apremilast"
      },
      {
        "code" : "15625451000119105",
        "display" : "Long-term current use of tofacitinib"
      },
      {
        "code" : "15929341000119102",
        "display" : "Long-term current use of antipsychotic medication"
      },
      {
        "code" : "15929381000119107",
        "display" : "Long-term current use of anxiolytic medication"
      },
      {
        "code" : "15929421000119103",
        "display" : "Long-term current use of antiviral agent"
      },
      {
        "code" : "15929461000119108",
        "display" : "Long-term current use of leuprorelin"
      },
      {
        "code" : "15929581000119100",
        "display" : "Long-term current use of antidepressant medication"
      },
      {
        "code" : "161646004",
        "display" : "H/O: high risk medication"
      },
      {
        "code" : "161647008",
        "display" : "H/O: anticoagulant therapy"
      },
      {
        "code" : "161648003",
        "display" : "H/O: steroid therapy"
      },
      {
        "code" : "161649006",
        "display" : "H/O: insulin therapy"
      },
      {
        "code" : "161650006",
        "display" : "H/O: anticonvulsant therapy"
      },
      {
        "code" : "161652003",
        "display" : "H/O: hormone replacement (HRT)"
      },
      {
        "code" : "161653008",
        "display" : "H/O: chemotherapy"
      },
      {
        "code" : "16234971000119108",
        "display" : "Long-term current use of diuretic"
      },
      {
        "code" : "16526761000119100",
        "display" : "Long-term current use of secukinumab"
      },
      {
        "code" : "16659291000119100",
        "display" : "Long-term current use of levothyroxine"
      },
      {
        "code" : "16716541000119101",
        "display" : "Long-term current use of oral hypoglycemic agent"
      },
      {
        "code" : "16755631000119109",
        "display" : "Long-term current use of natalizumab"
      },
      {
        "code" : "16755671000119107",
        "display" : "Long-term current use of mesalamine"
      },
      {
        "code" : "16772161000119102",
        "display" : "Long-term current use of vedolizumab"
      },
      {
        "code" : "16772201000119107",
        "display" : "Long-term current use of everolimus"
      },
      {
        "code" : "16863441000119108",
        "display" : "Long-term current use of stimulant"
      },
      {
        "code" : "16863481000119103",
        "display" : "Long-term current use of benzodiazepine"
      },
      {
        "code" : "16890821000119107",
        "display" : "Long-term current use of ixekizumab"
      },
      {
        "code" : "170622002",
        "display" : "Oral steroids started"
      },
      {
        "code" : "170624001",
        "display" : "Oral steroids stopped"
      },
      {
        "code" : "170688000",
        "display" : "Lithium stopped"
      },
      {
        "code" : "170689008",
        "display" : "Injectable phenothiazine stopped"
      },
      {
        "code" : "170919001",
        "display" : "Warfarin therapy stopped"
      },
      {
        "code" : "170920007",
        "display" : "Warfarin therapy started"
      },
      {
        "code" : "170954008",
        "display" : "Hormone replacement therapy contraindicated"
      },
      {
        "code" : "170955009",
        "display" : "Hormone replacement therapy started"
      },
      {
        "code" : "170958006",
        "display" : "Hormonal replacement therapy stopped"
      },
      {
        "code" : "174236121000119109",
        "display" : "Long-term current use of baricitinib"
      },
      {
        "code" : "182834008",
        "display" : "Drug course completed"
      },
      {
        "code" : "182840001",
        "display" : "Drug treatment stopped - medical advice"
      },
      {
        "code" : "182841002",
        "display" : "Doctor stopped drugs - ineffective"
      },
      {
        "code" : "182842009",
        "display" : "Doctor stopped drugs - side effect"
      },
      {
        "code" : "182843004",
        "display" : "Doctor stopped drugs - inconvenient"
      },
      {
        "code" : "182844005",
        "display" : "Doctor stopped drugs - patient dislikes"
      },
      {
        "code" : "182845006",
        "display" : "Doctor stopped drugs - avoid interaction"
      },
      {
        "code" : "182846007",
        "display" : "Doctor stopped drugs - medical aim achieved"
      },
      {
        "code" : "182862001",
        "display" : "Drug not taken - dislike taste"
      },
      {
        "code" : "182863006",
        "display" : "Drug not taken - dislike form"
      },
      {
        "code" : "182864000",
        "display" : "Drug not taken - side-effects"
      },
      {
        "code" : "182865004",
        "display" : "Drug not taken - inconvenient"
      },
      {
        "code" : "182868002",
        "display" : "Treatment stopped - alternative therapy undertaken"
      },
      {
        "code" : "182869005",
        "display" : "Drug not taken - patient lost tablets"
      },
      {
        "code" : "182870006",
        "display" : "Drug discontinued - reason unknown"
      },
      {
        "code" : "182871005",
        "display" : "Drug discontinued - patient fear/risk"
      },
      {
        "code" : "182872003",
        "display" : "Drug discontinued - too expensive"
      },
      {
        "code" : "182873008",
        "display" : "Drug treatment stopped - patient ran out of tablets"
      },
      {
        "code" : "182874002",
        "display" : "Treatment stopped - patient unable to concentrate"
      },
      {
        "code" : "21651000175103",
        "display" : "Antibiotic prophylaxis declined"
      },
      {
        "code" : "21681000175107",
        "display" : "Antihypertensive therapy declined"
      },
      {
        "code" : "236894121000119100",
        "display" : "Long term current use of canakinumab therapy"
      },
      {
        "code" : "253099801000119101",
        "display" : "Long term current use of mepolizumab"
      },
      {
        "code" : "266710000",
        "display" : "Drugs not taken/completed"
      },
      {
        "code" : "266711001",
        "display" : "Drug not taken - problem swallowing"
      },
      {
        "code" : "274512008",
        "display" : "Medication discontinued"
      },
      {
        "code" : "275929009",
        "display" : "Tablets too large to swallow"
      },
      {
        "code" : "279505881000119107",
        "display" : "Long-term current use of intranasal steroid"
      },
      {
        "code" : "309632008",
        "display" : "Thyroxine treatment started"
      },
      {
        "code" : "309841001",
        "display" : "Thyroxine treatment stopped"
      },
      {
        "code" : "312451002",
        "display" : "Aspirin prophylaxis contra-indicated"
      },
      {
        "code" : "315020006",
        "display" : "Beta blocker therapy declined"
      },
      {
        "code" : "315022003",
        "display" : "Nicotine replacement therapy declined"
      },
      {
        "code" : "315023008",
        "display" : "Aspirin prophylaxis declined"
      },
      {
        "code" : "315062004",
        "display" : "Beta blocker contraindicated"
      },
      {
        "code" : "315364008",
        "display" : "Angiotensin converting enzyme inhibitors contraindicated"
      },
      {
        "code" : "315604002",
        "display" : "Missed contraceptive pill"
      },
      {
        "code" : "328941000119101",
        "display" : "Long-term current use of bisphosphonates"
      },
      {
        "code" : "329061000119105",
        "display" : "Long-term current use of belimumab"
      },
      {
        "code" : "329071000119104",
        "display" : "Long-term current use of tocilizumab"
      },
      {
        "code" : "347841000119106",
        "display" : "Long-term current use of cannabis"
      },
      {
        "code" : "379562701000119103",
        "display" : "History of testosterone therapy"
      },
      {
        "code" : "390914001",
        "display" : "Thrombolytic therapy declined"
      },
      {
        "code" : "391158008",
        "display" : "Antibiotic prophylaxis recommended"
      },
      {
        "code" : "391159000",
        "display" : "Antibiotic prophylaxis not recommended"
      },
      {
        "code" : "394888000",
        "display" : "Hormone replacement therapy requested"
      },
      {
        "code" : "394987009",
        "display" : "Angiotensin II receptor antagonists contraindicated"
      },
      {
        "code" : "395006008",
        "display" : "Medication stopped - interaction"
      },
      {
        "code" : "395007004",
        "display" : "Medication stopped - ineffective"
      },
      {
        "code" : "395008009",
        "display" : "Medication stopped - contra-indication"
      },
      {
        "code" : "395009001",
        "display" : "Medication stopped - side effect"
      },
      {
        "code" : "395176007",
        "display" : "Bupropion declined"
      },
      {
        "code" : "401084003",
        "display" : "Angiotensin II receptor antagonist declined"
      },
      {
        "code" : "401244004",
        "display" : "H/O: prolonged corticosteroid therapy"
      },
      {
        "code" : "405165221000119107",
        "display" : "Long-term current use of belantamab mafodotin"
      },
      {
        "code" : "407572003",
        "display" : "Angiotensin II receptor antagonist not indicated"
      },
      {
        "code" : "408339001",
        "display" : "Thrombolysis therapy not indicated"
      },
      {
        "code" : "408354007",
        "display" : "Drug treatment still needed"
      },
      {
        "code" : "408355008",
        "display" : "Drug treatment no longer needed"
      },
      {
        "code" : "408795007",
        "display" : "Vitamin K prophylaxis declined"
      },
      {
        "code" : "412782003",
        "display" : "Inappropriate medication stopped"
      },
      {
        "code" : "413555000",
        "display" : "Antibiotic prophylaxis indicated"
      },
      {
        "code" : "413558003",
        "display" : "Anticoagulation contraindicated"
      },
      {
        "code" : "413559006",
        "display" : "Anticoagulation declined"
      },
      {
        "code" : "413560001",
        "display" : "Anticoagulation not indicated"
      },
      {
        "code" : "416126007",
        "display" : "Bisphosphonates declined"
      },
      {
        "code" : "416404000",
        "display" : "Angiotensin converting enzyme inhibitor target dose not achieved"
      },
      {
        "code" : "416702871000119106",
        "display" : "Long-term current use of sarilumab"
      },
      {
        "code" : "417576009",
        "display" : "Deferred antibiotic therapy"
      },
      {
        "code" : "430279008",
        "display" : "Drug treatment stopped at end of clinical trial"
      },
      {
        "code" : "434611000124106",
        "display" : "Maternal antenatal administration of corticosteroids for fetal lung maturation"
      },
      {
        "code" : "438553004",
        "display" : "History of drug therapy"
      },
      {
        "code" : "439631004",
        "display" : "History of statin therapy"
      },
      {
        "code" : "440935004",
        "display" : "History of beta adrenergic receptor blocking agent therapy"
      },
      {
        "code" : "440991005",
        "display" : "History of nitrate therapy"
      },
      {
        "code" : "441195008",
        "display" : "History of angiotensin converting enzyme inhibitor therapy"
      },
      {
        "code" : "441196009",
        "display" : "History of angiotensin II receptor antagonist therapy"
      },
      {
        "code" : "441899004",
        "display" : "History of therapy with ototoxic medication"
      },
      {
        "code" : "473151000",
        "display" : "History of tuberculosis drug therapy"
      },
      {
        "code" : "483574341000119108",
        "display" : "Long-term current use of upadacitinib"
      },
      {
        "code" : "53081000119101",
        "display" : "Long-term current use of testosterone replacement therapy"
      },
      {
        "code" : "548197911000119104",
        "display" : "Long-term current use of proton pump inhibitor therapy"
      },
      {
        "code" : "564231491000119106",
        "display" : "Long term current use of voclosporin"
      },
      {
        "code" : "584833311000119102",
        "display" : "Long-term current use of guselkumab"
      },
      {
        "code" : "61251000119108",
        "display" : "Long-term current use of tacrolimus"
      },
      {
        "code" : "61261000119105",
        "display" : "Long-term current use of sirolimus"
      },
      {
        "code" : "672601000119103",
        "display" : "Long-term current use of auranofin"
      },
      {
        "code" : "672611000119100",
        "display" : "Long-term current use of telaprevir"
      },
      {
        "code" : "686976671000119100",
        "display" : "History of human immunodeficiency virus pre-exposure prophylaxis"
      },
      {
        "code" : "69521000119101",
        "display" : "Long-term current use of thyroid hormone replacement therapy"
      },
      {
        "code" : "698428006",
        "display" : "Angiotensin II receptor antagonist indicated"
      },
      {
        "code" : "698449007",
        "display" : "Antibiotic therapy indicated"
      },
      {
        "code" : "698459008",
        "display" : "Antidepressant drug treatment stopped"
      },
      {
        "code" : "698460003",
        "display" : "Antiviral therapy declined"
      },
      {
        "code" : "698468005",
        "display" : "Bisoprolol contraindicated"
      },
      {
        "code" : "698758004",
        "display" : "Nebivolol therapy declined"
      },
      {
        "code" : "699008007",
        "display" : "History of fenfluramine therapy"
      },
      {
        "code" : "699137009",
        "display" : "Carvedilol therapy declined"
      },
      {
        "code" : "700110004",
        "display" : "Bisphosphonate prophylaxis suspended"
      },
      {
        "code" : "700384008",
        "display" : "Antibiotic prophylaxis not indicated"
      },
      {
        "code" : "702542006",
        "display" : "Incretin mimetic therapy started"
      },
      {
        "code" : "703989007",
        "display" : "Teriparatide therapy declined"
      },
      {
        "code" : "703991004",
        "display" : "Raloxifene therapy declined"
      },
      {
        "code" : "703996009",
        "display" : "Teriparatide not indicated"
      },
      {
        "code" : "703997000",
        "display" : "Teriparatide contraindicated"
      },
      {
        "code" : "703999002",
        "display" : "Raloxifene contraindicated"
      },
      {
        "code" : "704000000",
        "display" : "Raloxifene not indicated"
      },
      {
        "code" : "704033005",
        "display" : "Phosphodiesterase 5 inhibitor not indicated"
      },
      {
        "code" : "704047009",
        "display" : "Phosphodiesterase 5 inhibitor declined"
      },
      {
        "code" : "707298000",
        "display" : "Phosphodiesterase-5 inhibitor contraindicated"
      },
      {
        "code" : "70732231000132107",
        "display" : "Duplicate drug therapy stopped"
      },
      {
        "code" : "708000007",
        "display" : "Insulin treatment stopped"
      },
      {
        "code" : "710159007",
        "display" : "Long-term current use of immunosuppressive drug"
      },
      {
        "code" : "710814002",
        "display" : "Long-term current use of drug therapy"
      },
      {
        "code" : "710815001",
        "display" : "Long-term current use of insulin"
      },
      {
        "code" : "710816000",
        "display" : "Long-term current use of steroid"
      },
      {
        "code" : "710817009",
        "display" : "Long-term current use of inhaled steroid"
      },
      {
        "code" : "711149003",
        "display" : "Long-term current use of antibiotic"
      },
      {
        "code" : "711150003",
        "display" : "Long-term current use of anticoagulant"
      },
      {
        "code" : "711370000",
        "display" : "Oral steroids used since last encounter"
      },
      {
        "code" : "711436000",
        "display" : "Inhaled steroids used daily"
      },
      {
        "code" : "720971004",
        "display" : "Insulin declined"
      },
      {
        "code" : "721872002",
        "display" : "Antifungal therapy indicated"
      },
      {
        "code" : "721912451000119106",
        "display" : "Long-term current use of risankizumab"
      },
      {
        "code" : "726806751000119107",
        "display" : "Long-term current use of antimetabolite"
      },
      {
        "code" : "736004008",
        "display" : "Nebivolol contraindicated"
      },
      {
        "code" : "736006005",
        "display" : "Carvedilol contraindicated"
      },
      {
        "code" : "736799004",
        "display" : "Beta blocker target dose not achieved"
      },
      {
        "code" : "7611000175100",
        "display" : "Dipyridamole contraindicated"
      },
      {
        "code" : "763323007",
        "display" : "Hormone replacement therapy declined"
      },
      {
        "code" : "763897009",
        "display" : "Antineoplastic chemotherapy regimen declined"
      },
      {
        "code" : "764639002",
        "display" : "Antidepressant drug treatment started"
      },
      {
        "code" : "768231311000119101",
        "display" : "Long-term current use of calcineurin inhibitor"
      },
      {
        "code" : "787928003",
        "display" : "Coagulation factor Xa inhibitor prophylaxis indicated"
      },
      {
        "code" : "787930001",
        "display" : "Direct thrombin inhibitor prophylaxis indicated"
      },
      {
        "code" : "821378911000119105",
        "display" : "Long term current use of avacopan"
      },
      {
        "code" : "824522871000119100",
        "display" : "History of chimeric antigen receptor T-cell immunotherapy"
      },
      {
        "code" : "836671891000119108",
        "display" : "Long-term current use of belatacept"
      },
      {
        "code" : "840596001",
        "display" : "History of platelet aggregation inhibitor therapy"
      },
      {
        "code" : "840597005",
        "display" : "Long term dual platelet aggregation inhibitor therapy indicated"
      },
      {
        "code" : "840598000",
        "display" : "Platelet aggregation inhibitor therapy contraindicated"
      },
      {
        "code" : "897019004",
        "display" : "Antiviral prophylaxis recommended"
      },
      {
        "code" : "897020005",
        "display" : "Antifungal prophylaxis recommended"
      },
      {
        "code" : "897021009",
        "display" : "Antifungal prophylaxis not recommended"
      },
      {
        "code" : "897022002",
        "display" : "Antiviral prophylaxis not recommended"
      },
      {
        "code" : "972426521000119100",
        "display" : "Long term current use of anifrolumab"
      },
      {
        "code" : "98001000119105",
        "display" : "Long-term current use of anticonvulsant"
      }]
    }]
  }
}